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Influence of Two Different Beta‐Adrenergic Blocking Agents on the Increase in Fibrinolytic Activity and Factor VIII Activity during Submaximum and Maximum Exercise
Author(s) -
KorsanBengtsen Kristoffer,
Conradson ThorBjörn
Publication year - 1974
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1974.tb00285.x
Subject(s) - propranolol , endocrinology , medicine , chemistry
Oral administration of the beta‐adrenergic blocking agents alprenol and propranolol did not influence the increase in factor VIII and fibrinolytic activity during sub‐maximum and maximum physical exercise. During a submaximum work a continuous increase both in factor VIII and fibrinolytic activity was seen. In the following 30 min period of rest the fibrinolytic activity decreased while the factor VIII activity remained high. A maximum work load at the end of the resting period gave rise to a new increase both in factor VIII and fibrinolytic activity. Thus submaximum work of long duration did not abolish the ability to respond with increase in factor VIII and fibrinolytic activity in connection with a maximum work load.