Premium
Simple, Semiquantitative Test for Partial Factor XI11 (FSF) Deficiency
Author(s) -
Jakobsen E.,
Godal H. C.
Publication year - 1974
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1974.tb00222.x
Subject(s) - urea , factor ix , chemistry , endocrinology , medicine , chromatography , biochemistry
When the factor XIII concentration in plasma was less than 25–30 % of normal, clots made from citrated plasma by addition of thrombin (but without addition of calcium) dissolved completely in 5 M urea. Since, partial deficiency in factor XI11 may contribute to bleeding, the present procedure might be useful as a screening for such deficiencies.