Premium
Study on the Fibrillar Formation Surrounding the Nuclear Bridge in Some Types of Leukaemic Cells
Author(s) -
Ito S.,
Hatiom A.
Publication year - 1974
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1974.tb00217.x
Subject(s) - microfilament , microbiology and biotechnology , cell division , nucleus , anatomy , electron microscope , biology , cell , chemistry , cytoskeleton , biochemistry , physics , optics
Rieder cells which had a characteristically lobulated nucleus with a deep cleft were studied by both conventional and ultra‐high voltage electron microscopes in one case of acute granulocytic leukaemia and two cases of acute promyelocytic leukaemia. Light microscopically a few leukaemic cells in these cases possessed two nuclei. It was demonstrated that a bundle of microfilaments tightly surrounded the nuclear bridge of the Rieder cell. This finding seemed to be strikingly similar to that of the amphibian amitotic cell division observed by Pehlemann although origination of a bundle of microfilaments from the centriole and a process of cell division following the amitotic nuclear division could not be confirmed. Considering the possible contractile property of the microfilaments described hitherto in other types of cells, it is postulated that the Rieder cell in these types of leukaemia was produced by a process of abortive amitosis caused by the contraction of the microfilaments.