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Blood Lymphocytes in Hodgkin's Disease Increase of B‐Lymphocytes Following Extended Field Irradiation
Author(s) -
Engeset Arnfinn,
Fröland Stig S.,
Bremer Karl,
Høst Herman
Publication year - 1973
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1973.tb00116.x
Subject(s) - peripheral blood , lymphocyte , antibody , immunology , peripheral , medicine , irradiation , pathology , physics , nuclear physics
The percentage of B‐lymphocytes in peripheral blood has been investigated in 23 patients with Hodgkin's disease. About 2/3 of the patients were untreated. The others had been given extended field irradiation 5–36 months previously. Membrane‐bound immunoglobulin was utilized as a marker of B‐lymphocytes. In the untreated group about 1/2 of the patients were lymphocytopenic. The fraction of B‐lymphocytes was the same as has been found in healthy controls, which was on the average about 10 % of the blood lymphocytes. In the irradiated group the peripheral lymphocyte counts were normal. The fraction of B‐lymphocytes was considerably increased and comprised on the average about 34%.