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Immunological Characterization of Anti‐Haemophilic Factor A Related Antigen in Haemophilia A
Author(s) -
Bouma B. N.,
Mourik J. A.,
Wiegerinck Y.,
Sixma J. J.,
Mochtar I. A.
Publication year - 1973
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1973.tb00114.x
Subject(s) - haemophilia a , antiserum , haemophilia , antigen , immunology , haemophilia b , antibody , medicine , virology , pediatrics
The properties of an antiserum prepared against a factor VIII related antigen, isolated from haemophilic plasma, were investigated and compared with those of anti‐normal factor VIII. No difference could be observed between these antisera. The results suggest that in haemophilic plasma a factor VIII molecule is present with the same antigenic determinants as normal factor VIII although factor VIII activity is lacking.