Premium
Levels of Transcobalamin II in Normal Human Serum: Measured with Zirconyl Phosphate Gel
Author(s) -
Sonneborn David W.,
Baskerville Ann B.,
Regelson William
Publication year - 1973
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1973.tb00090.x
Subject(s) - phosphate , chemistry , biochemistry
Zirconyl phosphate gel at pH 6.25 binds selectively to transcobalamin II and not to transcobalamin I. Using this technique, levels of TC‐II in 100 normal donors were determined to be 0.96 ± 0.2 ng of B 12 bound per ml of serum. The stability of TC‐II at various temperatures, the lack of any difference between levels of TC‐II in males and females, and the lack of fluctuation of levels of TC‐II in any one individual's serum are shown.