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Erythrocyte Glutathione Reductase Activity in Chronic Renal Disease
Author(s) -
Ferrone S.,
Zanella A.,
Sirchia G.
Publication year - 1970
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1970.tb01924.x
Subject(s) - chronic renal failure , glutathione reductase , glutathione , medicine , renal function , chronic renal disease , chronic pyelonephritis , gastroenterology , red cell , disease , glomerulonephritis , enzyme , endocrinology , glutathione peroxidase , kidney , chemistry , biochemistry
Red cell glutathione reductase activity has been investigated in 79 patients suffering from chronic pyelonephritis or chronic glomerulonephritis. Of the two groups of patients considered, those in the first group were anaemic and had marked renal failure, while those in the second had a haemoglobin equal or above 11 g/100 ml with in most cases slight renal function impairment. Enzyme activity was found significantly above normal in nephropatic subjects, being significantly higher in anaemic than in non‐anaemic patients.