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RNA Content of Megaloblasts in Pernicious Anaemia
Author(s) -
Wickramasinghe S. N.
Publication year - 1970
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1970.tb01920.x
Subject(s) - erythropoiesis , metachromasia , rna , pernicious anaemia , pernicious anemia , stain , biology , biochemistry , staining , immunology , medicine , anemia , genetics , gene
Azure B has been used as a metachromatic stain for the quantitative cytochemical estimation of total RNA in developing erythroblasts. The megaloblasts of pernicious anaemia show a progressive reduction of RNA with increasing maturity; the decrease being similar to that seen during normal erythropoiesis.