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Urinary Immunoglobulins in Patients With Cancer
Author(s) -
Lindström Folke D.,
Jr. Ralph C. Williams,
Theologides Athanasios
Publication year - 1970
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1970.tb01918.x
Subject(s) - bence jones protein , urinary system , antibody , medicine , immunoglobulin light chain , lymphoma , cancer , breast cancer , urine , kappa , pathology , immunology , gastroenterology , linguistics , philosophy
Urinary immunoglobulins were studied in 63 patients with different types of cancer. The main object was to investigate the occurrence of monoclonal immunoglobulins, primarily of the Bence Jones type, in the urine. Cancer of the breast dominated in the group as a whole (23 cases), and different forms of gastrointestinal cancer dominated among the remaining cases. Elevated levels of urinary light chains were discovered in 8 out of 63 patients. A marked predominance of kappa‐type light chains was noted, similar to what has been observed in leukaemia and lymphoma. However, they lacked the electrophoretic homogeneity of Bence Jones protein.