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Prenatal Assessment of Blood Group Antibodies Against ‘Public’ Antigens: An Example of Anti‐Ve (Vel) in Pregnancy
Author(s) -
Drachmann O.,
Lundsgaard Anne
Publication year - 1970
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1970.tb01866.x
Subject(s) - pregnancy , antibody , serology , medicine , antigen , isoantibodies , hemolytic disease of the newborn (abo) , immunology , coombs test , haemolytic disease , obstetrics , disease , fetus , biology , genetics
A review is given of the ante‐ and peri‐natal immunohaematological problems arising when ‘non‐Rhesus’ irregular red‐cell antibodies, especially those reacting with ‘public’ antigens, are encountered in pregnancy, and a case of anti‐Ve in pregnancy is reported. The antibody did not cause haemolytic disease of the newborn. The direct Coombs test was negative, and no maternal antibody was present in the infant's serum. The results of the serological and immunological investigations are discussed in relation to the condition of the newborn infant, and the difficulty in assessing whether an infant is likely to be affected when such antibodies are present in pregnancy is stressed.