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The Use of 75 Se‐Methionin for the in vivo Study of Platelet Kinetics
Author(s) -
Najean Y.,
Ardaillou N.
Publication year - 1969
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1969.tb01833.x
Subject(s) - platelet , in vivo , thrombocytosis , kinetics , labelling , chemistry , medicine , pharmacology , gastroenterology , biochemistry , biology , physics , microbiology and biotechnology , quantum mechanics
Platelet kinetics were studied using 75 Se‐methionin as an in vivo tracer in normal and aplasic rats and in normal man and in patients suffering from bone marrow inadequacy, thrombocytosis, thrombocytopenia due to hyperdestruction. Results are compared with those obtained with 51 Cr‐labelling. The method is found useful to measure both platelet production and autologous platelet life span in thrombocytopenic patients.