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Fibrinogen Turnover in Pregnancy
Author(s) -
Regoeczi E.,
Hobbs K. R.
Publication year - 1969
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1969.tb01823.x
Subject(s) - fibrinogen , catabolism , medicine , pregnancy , endocrinology , protein turnover , turnover , chemistry , biology , metabolism , biochemistry , protein biosynthesis , genetics , management , economics
15 turnover studies in 8 pregnant rhesus monkeys using iodine‐labelled fibrinogen showed that fractional catabolic rates of this protein were similar to those in control females, whereas the absolute catabolic rates were significantly elevated. Intermediate, non‐clottable labelled breakdown products of fibrinogen were present in the circulation of these monkeys. The implication of these findings are briefly discussed.