Premium
Studies on Two Patients with Concomitant Intrinsic Factor Secretory Defect and Jejunal Diverticulosis
Author(s) -
MurrayLyon Iain M.,
Finlayson Niall D. C.,
Shearman David J. C.
Publication year - 1968
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1968.tb01763.x
Subject(s) - intrinsic factor , diverticulosis , vitamin b12 , gastroenterology , medicine , concomitant , malabsorption , cyanocobalamin , endocrinology
Two cases of jejunal diverticulosis associated with intrinsic factor deficiency are reported. One case had megaloblastic anaemia and full correction of 58 Co vitamin B 12 absorption was achieved by broad spectrum antibiotic therapy alone. The second case had intrinsic factor deficiency and full correction of 58 Co vitamin B 12 absorption was achieved by the addition of oral intrinsic factor alone. The variable contribution made to the development of vitamin B 12 deficiency in jejunal diverticulosis by intrinsic factor deficiency and bacterial colonisation of the small intestine is discussed.