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Heavy Metals in the Granules of Eosinophilic Granulocytes
Author(s) -
Pihl E.,
Gustafson G. T.,
Josefsson B.,
Paul K.G.
Publication year - 1967
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1967.tb01639.x
Subject(s) - eosinophil , zinc , eosinophilic , metal , atomic absorption spectroscopy , chemistry , ultrastructure , heavy metals , biology , pathology , immunology , environmental chemistry , anatomy , medicine , physics , organic chemistry , quantum mechanics , asthma
An ultrastructural modification of the sulfide‐silver method disclosed that rat and cattle eosinophilic granulocytes contain heavy metals in the non‐crystalloid parts of their specific granules and possibly also in the cell membrane. Metal analysis of isolated granules by means of atomic absorption spectrophotometry indicated that the principal metal contained in the granules is zinc. Consequently the metal demonstrated ultrastructurally in eosinophil granules is thought to be zinc.