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Erythrocyte Transaminase Activity in Iron Deficiency Anaemia
Author(s) -
Cavill I. A. J.,
Jacobs A.
Publication year - 1967
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1967.tb01626.x
Subject(s) - transaminase , pyridoxine , pyridoxine deficiency , iron deficiency , medicine , cofactor , endocrinology , xanthurenic acid , excretion , chemistry , pyridoxal phosphate , biochemistry , anemia , enzyme , tryptophan , amino acid
There is a relative lack of the pyridoxal coenzyme for glutamic‐pyruvic transaminase in the erythrocytes of patients with iron deficiency anaemia compared with normal subjects. This group of patients also has an increased urinary excretion of xanthurenic acid following a tryptophane load. These findings suggest a minor degree of pyridoxine deficiency. Glutamic oxaloacetic transaminase appears to be more avid for the coenzyme and is unchanged in the iron deficient patients.