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The Influence of Hypercephalinaemia on the Adenosine Diphosphate Induced Thrombosis in the Rat
Author(s) -
Nordöy A.,
Chandler A. B.
Publication year - 1965
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1965.tb01290.x
Subject(s) - thrombosis , platelet , adenosine diphosphate , chemistry , adenosine , pharmacology , platelet aggregation , medicine , endocrinology , biochemistry
1. The influence of intravenously and intraperitoneally administered cephalin on ADP‐induced thrombosis in the rats was studied. 2. Hypercephalinaemia induced by simultaneous administration of cephalin with the ADP caused a significant increase in thrombosis. 3. The mode of action of phospholipids is discussed and it is concluded that phospholipids can act in thrombosis during the first stage of platelet adhesion.