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The Biphasic Appearance of Labelled Lymphocytes in the Blood after Single Injections of H 3 ‐Thymidine
Author(s) -
Lundmark Karl Martin,
Fichtelius KarlErik
Publication year - 1965
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1965.tb01284.x
Subject(s) - thymidine , chemistry , blood circulation , microbiology and biotechnology , medicine , immunology , biology , biochemistry , dna , traditional medicine
In earlier work Fichtelius (1951) demonstrated a biphasic appearance of labelled lymphocytes in the blood after a single injection of P 32 as orthophosphate. The second activity increase was at that time explained in three alternative ways: re‐circulation, reutilization or delayed output. This biphasic appearance of labelled lymphocytes in the blood was confirmed in this new study in rabbits using H 3 ‐thymidine. To‐day all three alternative explanations are still possible and more work is needed for a certain interpretation of the second activity peak observed.