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Metastatic small cell neuroendocrine carcinoma of the breast
Author(s) -
Boyd Alan S.,
Hayes Benjamin B.
Publication year - 2012
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2012.01970.x
Subject(s) - merkel cell carcinoma , medicine , pathology , immunohistochemistry , breast carcinoma , carcinoma , merkel cell , adenocarcinoma , neuroendocrine carcinoma , small cell carcinoma , neuroendocrine differentiation , breast cancer , metastasis , neuroendocrine tumors , oncology , cancer , prostate cancer
Cutaneous metastases from internal malignancies in women overwhelmingly emanate from the breast and typically exhibit features of an adenocarcinoma, although other histopathologic patterns may also be seen. Neuroendocrine breast carcinoma represents an uncommon variant of mammary carcinoma with fewer than 40 cases of the small cell subcategory reported. As with other small cell carcinomas, they may exhibit Merkel cell‐like features and appropriate diagnosis of these tumor deposits often turns on clinical history and an appropriate immunohistochemical profile. Herein, we report the first known patient with cutaneous metastases from a small cell neuroendocrine breast carcinoma.