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Cutaneous metastatic cholangiocarcinoma: a report of three cases and review of the literature
Author(s) -
West Kelly L.,
Selim Maria Angelica,
Puri Puja K.
Publication year - 2010
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2010.01619.x
Subject(s) - medicine , malignancy , metastasis , pathological , pathology , differential diagnosis , scalp , disease , immunohistochemistry , dermatology , cancer
Cutaneous metastasis from cholangiocarcinoma is an extremely rare event. Herein, we present three cases with review of the literature. Case 1 is that of a young female with scalp metastasis. Cases 2 and 3 involve cutaneous metastasis to the sites of prior biliary drains, one occurring in a young female with a history of multiple biliary surgeries and one in a male with a history of sclerosing cholangitis. Review of the literature shows that the presentation of cutaneous metastases from cholangiocarcinoma can vary in terms of anatomic location and clinical features. The pathological and immunohistochemical profile of metastatic cholangiocarcinoma can be non‐specific, and accurate diagnosis relies in part on clinical correlation. In summary, metastatic disease should always be included in the differential diagnosis of cutaneous lesions in patients with known malignancy. West KL, Selim MA, Puri PK. Cutaneous metastatic cholangiocarcinoma: a report of three cases and review of the literature.