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Intradermal proliferative fasciitis in childhood: a potential diagnostic pitfall
Author(s) -
Magro Gaetano,
Michal Michal,
Alaggio Rita,
D’ Amore Emanuele
Publication year - 2011
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2009.01460.x
Subject(s) - dermis , pathology , nodular fasciitis , medicine , malignancy , mitosis , fascia , dermatology , anatomy , differential diagnosis , biology , microbiology and biotechnology
Proliferative fasciitis (PF) is a pseudosarcomatous proliferation which typically occurs in the subcutaneous tissue and fascia. Although patients are characteristically middle‐aged people, occasionally PF can arise in children. Histologically, PF is characterized by a proliferation of large ganglion‐like and spindle‐shaped cells which, especially in childhood, may exhibit high mitotic activity, but no atypical mitoses. We report a case of PF in the dermis of a 13‐year‐old boy. This is the first case of PF primarily arising in the dermis. Apart from the unusual site, another intriguing finding was the presence of rare atypical mitoses, a feature which has not been previously emphasized in PF. Awareness that PF may occur in the dermis, exhibiting occasional atypical mitoses, is crucial to avoid a misdiagnosis of malignancy. Magro G, Michal M, Alaggio R, Amore ED. Intradermal proliferative fasciitis in childhood: a potential diagnostic pitfall.