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Signet ring squamous cell carcinoma–the forgotten variant: case report and review of the literature
Author(s) -
Demellawy Dina El,
Onuma Kazuya,
Alowami Salem
Publication year - 2011
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2009.01418.x
Subject(s) - basal cell , pathology , medicine , carcinoma , signet ring cell , dermatology , cancer , adenocarcinoma
Squamous cell carcinoma is one of the commonest skin cancers. In most instances, histological diagnosis is straightforward and does not pose any diagnostic challenge to the handling pathologist. We report a rare case of signet ring squamous cell carcinoma (SRSCC) occurring in an 84‐year‐old woman who presented with a sore on the upper lip. Excision of the lesion showed signet ring carcinoma within a scar and surface ulceration. Deeper sections showed focal area of squamous differentiation. Although rare, consideration of squamous cell carcinoma as a diagnosis of primary skin tumors with signet ring morphology, especially in the absence of history of adenocarcinoma, may prevent missing rare cases of SRSCCs. Demellawy DE, Onuma K, Alowami S. Signet ring squamous cell carcinoma–the forgotten variant: case report and review of the literature.