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Disseminated Scopulariopsis –culture is required to distinguish from other disseminated mould infections
Author(s) -
Swick Brian L.,
Reddy Sindhura C.,
Friedrichs Amanda,
Stone Mary Seabury
Publication year - 2010
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2009.01358.x
Subject(s) - medicine , pathology , bone marrow , aspergillosis , mycosis , dermatology , immunology
Disseminated fungal infections are a major cause of mortality in severely immunocompromised bone marrow transplant (BMT) patients. Scopulariopsis is a soil saprophytic mould that is typically associated with onychomycosis and only rarely associated with disseminated infection with cutaneous findings. We describe a case of fatal disseminated Scopulariopsis infection in a 56‐year‐old neutropenic male with chronic myelogenous leukemia status post peripheral blood stem cell transplant that was clinically and histologically indistinguishable from disseminated Aspergillus , Fusarium or zygomycosis infection. Distinguishing the above listed fungi by tissue culture is crucial because disseminated Scopulariopsis is difficult to eradicate and associated with a high mortality rate in the immunocompromised BMT patient population. Swick BL, Reddy SC, Friedrichs A, Stone MS. Disseminated Scopulariopsis –culture is required to distinguish from other disseminated mould infections.