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Epithelial sheath neuroma: be aware of benign perineural invasion!
Author(s) -
Husain Ehab A.,
AlDaraji Wael I.
Publication year - 2009
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2008.01068.x
Subject(s) - malignancy , perineurium , perineural invasion , neuroma , pathology , medicine , differential diagnosis , pathogenesis , dermatology , peripheral nerve , cancer , anatomy , surgery
Perineural involvement by epithelial cells is usually considered as a sign of malignancy and is seen in a variety of malignant skin neoplasms. However, there are other benign conditions characterized by the presence of perineural involvement by epithelial cells. We present a case of epithelial sheath neuroma in a 43‐year‐old male. The clinicopathological features of this newly described entity are discussed together with the differential diagnosis and the different hypotheses of pathogenesis. Both pathologists and dermatologists should be aware of this entity to avoid misdiagnosis of malignancy.