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Adult T‐cell leukemia/lymphoma in a patient from Romania: a case report and review of the literature
Author(s) -
Fett Nicole M.,
Siddiqui Jawed,
Creswell Caleb H.,
Zhang Dahua,
Lloyd Rita,
Wood Gary S.
Publication year - 2008
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2007.00962.x
Subject(s) - medicine , leukemia , ultraviolet b , lymphoma , dermatology , malignancy , refractory (planetary science) , adult t cell leukemia/lymphoma , pathology , t cell leukemia , immunology , biology , astrobiology
Adult T‐cell leukemia/lymphoma (ATLL) is a rare malignancy caused by human T‐cell leukemia virus‐1. ATLL is endemic to Japan, and to date, there are only four case reports of patients from Romania who have developed ATLL. Here, we describe a woman living in Madison, Wisconsin, originally from Romania, who presented with an atypical papulosquamous eruption and was ultimately diagnosed with smoldering ATLL. Narrow‐band ultraviolet‐B (UV‐B) therapy and mid‐potency topical steroids resulted in skin clearing for approximately 5 months after diagnosis; however, she subsequently relapsed with disease refractory to both narrow band UV‐B and psoralen plus ultraviolet A (PUV‐A), progressed to acute ATLL and expired secondary to complications.