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Collagenous spherulosis in an oral mucous cyst
Author(s) -
Henry Cathy Renee,
Nace Mindy,
Helm Klaus F.
Publication year - 2008
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2007.00824.x
Subject(s) - mucocele , pathology , medicine , salivary gland , cyst , extravasation , myoepithelial cell , epithelium , anatomy , immunohistochemistry
Collagenous spherulosis is a histological pattern that has been described in both benign and malignant salivary gland tumors, proliferative lesions of breast ductal epithelium, chondroid syringomas and schwannomas. Histologic structures of similar appearance have also been reported in oral extravasation mucoceles as questionable myxoglobulosis or myxoglobulosis‐like change. We report collagenous spherulosis within a mucocele removed from the lower lip of a 17‐year‐old female. Based upon histologic appearance, immunophenotypic data and review of the literature, we hypothesize that collagenous spherulosis and myxoglobulosis are morphologically related reaction patterns.