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Pilonidal sinus associated with cellular blue nevus. A previously unrecognized association
Author(s) -
ValBernal José Fernando,
GonzálezVela María Carmen,
Hermana Sandra,
Garijo María Francisca,
GonzálezLópez Marcos A.
Publication year - 2007
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2007.00753.x
Subject(s) - medicine , blue nevus , pathology , nodule (geology) , differential diagnosis , sinus (botany) , pathological , lesion , melanoma , nevus , dermatology , biology , paleontology , botany , cancer research , genus
A neoplasm associated with a pilonidal sinus (PS) is a rare occurrence in the course of a common disease. Early detection is imperative. To our knowledge, pilonidal disease associated with a cellular blue nevus (CBN) has not been reported. There is a 10% diagnostic error rate with this last lesion. Here we report the case of a 19‐year‐old man with recurrent sacrococcygeal PS infection associated with an indurated dome‐shaped blue‐black nodule 1.7 cm in diameter. Clinical diagnosis of the nodule was uncertain suggesting a pigmentary or a vascular tumor. A complete resection of the two lesions was achieved. Pathological study showed a CBN showing a predominantly alveolar pattern associated with a chronic pilonidal disease. The tumor cells showed diffuse strong reactivity for melan‐A and HMB‐45, and focal reactivity for S‐100 protein. Staining for Ki‐67 (MIB1) was virtually negative. Differential diagnoses included atypical CBN, borderline melanocytic tumor and malignant melanoma. Radical excision provides a good prognosis for the rare association consisting of a common disease such as PS with the uncommon CBN.