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Primary cutaneous meningioma of the scalp: a case report and review of literature
Author(s) -
Hussein Mahmoud R.,
Abdelwahed Ahmed Rezk
Publication year - 2007
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2007.00720.x
Subject(s) - pathology , cytokeratin , vimentin , desmin , meninges , meningioma , scalp , cd31 , cd34 , medicine , nodule (geology) , immunohistochemistry , immunostaining , anatomy , biology , paleontology , genetics , stem cell
Meningiomas of the skin are rare tumors that can pose considerable diagnostic challenges to the pathologist. This study presents a case of primary cutaneous meningioma in a newly born baby girl that presents with a subcutaneous nodule on the left posterior occipital scalp. A Magnetic Resonance Imaging examination failed to detect any communication between the tumor site and the meninges. The mass was excised and intra ‐operatively, there was no evidence of connection between the tumor and the underlying tissues. Microscopically, the tumor was composed of banal looking, mitotically inactive spindle‐shaped cells with a whorled configuration. Some cells were concentrically arranged around blood vessels. Immunohistochemical studies were positive for epithelial membrane antigen and vimentin. Immunostains for cytokeratin, S‐100 protein, vascular (CD34 and CD31) and muscle markers (Desmin and smooth muscle actin) were negative. The diagnosis of cutaneous meningioma was established. A review of literature was presented.