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Combined malignant melanoma and basal cell carcinoma tumor of the intermingled type
Author(s) -
BraunFalco Markus
Publication year - 2007
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2006.00703.x
Subject(s) - basal cell carcinoma , melanoma , pathology , lesion , medicine , superficial spreading melanoma , carcinoma , basal cell , cancer research
Background: The combination of malignant melanoma (MM) and basal cell carcinoma (BCC) within a single tumor is an unusual finding. Case report: An 84‐year‐old white man with a pigmented tumor on the back showing a combination of MM and BCC. Results: A 1.5 × 1.5‐cm irregular brown lesion on the back was clinically suggestive of MM. Histopathologically, the lesions turned out to be a combined tumor consisting of a superficial BCC and a regressive MM with a tumor thickness of 1.25 mm. The conglomerates of the BCC lay within the MM and were admixed with a high number of Melan‐A‐positive melanocytic cells. Conclusion: By reviewing the low number of published cases, we found that a combined MM‐BCC tumor exists in two variants: a collision type in which components of each cell type are clearly demarcated and an intermingled type in which both cell types grow intimately together. Although both types occur as a mere incidence, in particular, the intermingled type may be diagnostically challenging and the evaluation of its dignity may be questionable.