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Seborrheic keratosis with pseudorosettes and adamantinoid seborrheic keratosis: two new histopathologic variants
Author(s) -
Requena Luis,
Kutzner Heinz
Publication year - 2006
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2006.00528.x
Subject(s) - seborrheic keratosis , dermatology , keratosis , dermatopathology , medicine , pathology , skin tumor , actinic keratosis , cancer , basal cell , carcinogenesis
Aims: Seborrheic keratoses are the most common benign cutaneous neoplasms in adult and middle‐age patients. There are six distinctive histopathologic variants of seborrheic keratosis, namely, acanthotic or solid, reticulated or adenoid, hyperkeratotic or papillomatous, clonal or nested, irritated and inflamed. Methods: We report two additional histopathologic variants of seborrheic keratosis. Results: One lesion showed abundant intercellular mucin, closely resembling to adamantinoma, and therefore was named adamantinoid seborrheic keratosis. The other one exhibited a peculiar distribution of the basaloid keratinocytes, which were arranged radially around small central spaces, resulting in pseudorosette formation. Discussion: To our knowledge, these two histopathologic variants of seborrheic keratosis have been not previously described in the literature.