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Cutaneous involvement by angioimmunoblastic T‐cell lymphoma: a unique histologic presentation, mimicking an infectious etiology
Author(s) -
Jayaraman Anu G.,
Cassarino David,
Advani Ranjana,
Kim Youn H.,
Tsai Eunice,
Kohler Sabine
Publication year - 2006
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.2006.00489.x
Subject(s) - pathology , medicine , lymphoma , etiology , histiocyte , lymph node , erythroderma , angioimmunoblastic t cell lymphoma , cutaneous lymphoma , purpura (gastropod) , dermatology , mycosis fungoides , t cell , biology , immunology , ecology , immune system
Angioimmunoblastic T‐cell lymphoma (AILT) is an aggressive peripheral T‐cell lymphoma that is frequently accompanied by a cutaneous eruption. The cutaneous findings most commonly consist of a maculopapular eruption on the trunk. However, purpura, infiltrated or urticarial plaques, papulovesicular lesions, nodules, and erythroderma have also been reported. Histologic findings in the lymph node are characteristic, while those in the skin may show one of four patterns. Here, we review the previously reported histologic patterns and present a case of AILT involving the skin with a unique histologic appearance of necrotizing granulomas with abundant histiocytes and eosinophils, mimicking an infectious etiology.