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Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: A case report
Author(s) -
Lele Subodh M.,
Gloster Elizabeth S.,
Heilman Edward R.,
Chen Patrick C.,
Chen ChunKuo,
Anzil Archinto P.,
Pozner Jason N.,
Reardon Michael J.
Publication year - 1997
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1997.tb01576.x
Subject(s) - pathology , immunohistochemistry , basal cell , dorsum , medicine , lesion , neoplasm , anatomy
A 91‐year‐old man presented with a 9.0 × 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque‐like lesion that had been present for many years. He had similar long‐standing hyperkeratotic plaque‐like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well‐differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.