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Pigmented epidermotropic ductal carcinoma of the breast in a male
Author(s) -
FernándezFigueras M. T.,
Puig L.,
Casanova J. M.,
Musulén E.,
MatíasGuiu X.,
NavasPalacios J. J.
Publication year - 1995
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1995.tb00750.x
Subject(s) - pathology , stroma , immunohistochemistry , melanosome , areola , medicine , carcinoma , lesion , melanin , biology , genetics
The first case of pigmented epidermotropic breast carcinoma in a male, presenting as a pigmented lesion of the areola and nipple, is described. Immunohistochemical and ultrastructural studies demonstrated that the pigmentation was found to be primarily due to colonization of tumor nests by melanocytes, with numerous melanophages interspersed in the desmoplastic stroma and only occasional compound melanosomes within the epithelial tumor cells.