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Sclerotic fibroma: A fossil no longer
Author(s) -
McCalmont Timothy H.
Publication year - 1994
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1994.tb00696.x
Subject(s) - fibroma , immunoperoxidase , pathology , medicine , stage (stratigraphy) , neoplasm , biology , antibody , paleontology , immunology , monoclonal antibody
We report on a patient with a sclerotic Fibroma that recurred 30 months after initial removal. The histologic features were characteristic, and immunoperoxidase stains using primary antibodies directed against cell proliferation markers were positive in a significant proportion of the neoplastic nuclei. A review of the literature identified one other sclerotic fibroma that persisted. These clinical and light microscopic features support the interpretation that sclerotic fibroma is a proliferating neoplasm with an unusual histologic pattern, rather than the end‐stage of a process that was formerly more cellular. We advocate use of sclerotic fibroma as the preferred diagnostic term.