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Cutaneous lymphadenoma with focal mucinosis
Author(s) -
Wechsler Janine,
Fromont Gaelle,
André JeanMichel,
Zafrani Elie S.
Publication year - 1992
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1992.tb01356.x
Subject(s) - reticular dermis , pathology , hair follicle , mucinosis , stroma , dermis , stromal cell , keratin , epidermis (zoology) , anatomy , reticular connective tissue , biology , reticular fiber , medicine , immunohistochemistry , microbiology and biotechnology
Cutaneous lymphadenoma of the eyebrow occurred in a 72‐year‐old man. The nodular tumor was well circumscribed but non encapsulated and invaded the reticular dermis and superficial hypodermis without any connection with the epidermis. Tumor cells had a basal‐like appearance and were arranged in small lobules and islands with peripheral palisading and areas of central keratinization. They were often dissociated by an extracellular mucinous material. The stroma was fibroblastic and contained a marked lymphoid infiltrate that surrounded and penetrated the neoplastic lobules. Occasional germ‐like hair follicle structures were noted. The immunohistocheimical pattern was similar to that of hair follicles, and the leucocytic component was predominantly composed of T‐Iymphocytes and Langerhans cells, which were specially numerous within the neoplastic lobules. We believe that the tumor, in the present case, has morphologic features consistent with epithelial and stromal attributes observed in hair follicles.