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Irritated seborrheic keratoses and benign verrucous acanthomas do not contain papillomavirus DNA
Author(s) -
Zhu WenYuan,
Leonardi Craig,
Kinsey Willian,
Penneys Neal S.
Publication year - 1991
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1991.tb01383.x
Subject(s) - actinic keratoses , dermatology , seborrheic keratosis , human papillomavirus , pathology , medicine , keratosis , papillomaviridae , cancer , basal cell , cervical cancer
Sections from paraffin‐embedded tissues of lesions thought to represent verrucous lesions (benign verrucous acanthomas: BVA) as well as materials from controls including seborrheic keratoses (SK), irritated SK, and verruca vulgaris from areas other than the genitalia were analyzed for the presence of multiple human papillomaviruses (HPV) including types 6, 11, 16, 18, and 33 using DNA amplification methodology. HPV DNA sequences were not found in amplified samples of BVA, SK, and irritated SK samples, but were identified in those obtained from verruca vulgaris. Our results suggest that BVA, SK, and irritated SK are generally not associated with HPV DNA even though certain of these lesions may histologically mimic the architecture of verruca.