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Majocchi's granuloma
Author(s) -
Smith K. J.,
Neafie R. C.,
Skelton H. G.,
Barrett T. L.,
Graham J. H.,
Lupton G. P.
Publication year - 1991
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1991.tb00598.x
Subject(s) - granuloma , dermatophyte , biology , pathology , trichophyton rubrum , microsporum canis , dermatology , antifungal , medicine , microbiology and biotechnology
Majocchi's granuloma (nodular granulomatous perifolliculitis) is a well recognized but uncommon infection of dermal and subcutaneous tissue by fungal organisms (dermatophytes) usually limited to the superficial epidermis. The organism usually associated with Majocchi's granuloma is Trichophylon rubrum ; however, other dermatophytes including T. mentagrophytes (variety granulosum ), T. epilans , T. violaceum , M. audouinii , M. gypseum , M. ferrugineum , and M. canis may be the causative agent. A review of 17 cases revealed not only the variety of possible organisms but also a marked variation from the usual hyphal forms. The morphologic variations including yeast forms, bizarre hyphae, mucinous coatings, and the Splendore‐Hoeppeli phenomenon may be factors which allow the dermatophytes to persist and grow in an abnormal location. Also, there is evidence that Majocchi's granuloma may occur in two distinct groups of patients.