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Pericapillary fibrin cuff: a histological sign of venous leg ulceration
Author(s) -
Vanscheidt W.,
Laaff H.,
Wokalek H.,
Niedner R.,
Schöpf E.
Publication year - 1990
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1990.tb00100.x
Subject(s) - medicine , fibrin , cuff , venous stasis , pathogenesis , pathology , etiology , surgery , immunology
The incidence of pericapillary fibrin cuffs was investigated in 49 biopsies of venous leg ulcers and 67 biopsies of leg ulcers of non‐venous etiology. Pericapillary fibrin cuffs were seen in 28 biopsies (57.1%) of venous leg ulcers, but only in 11 biopsies (16.4%) of non‐venous leg ulcers. In the venous leg ulcers pericapillary fibrin cuffs occurred predominantly near the ulcer surface and around dilated capillaries. Dilation of the capillaries and inflammation probably contribute more to the pathogenesis of pericapillary fibrin cuffs than venous hypertension.