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Atypical fibroxanthoma: two unusual variants
Author(s) -
Wilson P. R.,
Strutton G. M.,
Stewart M. R.
Publication year - 1989
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1989.tb00017.x
Subject(s) - atypical fibroxanthoma , giant cell , pathology , osteoclast , chondrosarcoma , immunohistochemistry , soft tissue , biology , medicine , biochemistry , in vitro
Two unusual fibroxanthomas were studied by light microscopy. The first case contained numerous osteoclast‐like cells and resembled malignant giant cell tumour of soft tissues, a variant of malignant fibrous histiocytoma. Osteoclast‐like giant cells were negative for lysozyme and alpha‐1‐antitrypsin. The second case contained areas of chondroid differentiation which resembled chondrosarcoma. Tumour cells within the cartilaginous areas were positive for S100 protein.