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Human papillomavirus Type 2 DNA in oral and labial verruca vulgaris
Author(s) -
Eversole L. R.,
Laipis P. J.,
Green T. L.
Publication year - 1987
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1987.tb01531.x
Subject(s) - capsid , verruca vulgaris , human papillomavirus , antigen , biology , virology , genome , in situ hybridization , dna , nucleic acid thermodynamics , virus , dermatology , pathology , gene , medicine , immunology , genetics , base sequence , gene expression
Twenty instances of verruca vulgaris, equally divided between oral mucosa and lip vermillion, were assayed for the presence of human papillomavirus (HPV) capsid antigen and type‐specific DNA employing in situ hybridization methods. All 10 cases arising on lip vermilion expressed capsid antigen and harbored HPV Type 2 genomes as assessed under conditions of high stringency DNA hybridization. Oral verrucae rarely expressed capsid antigen; HPV Type 2 genomes were encountered in 20% of the cases.