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Neurotropic melanoma of the face invading the maxillary nerve
Author(s) -
Warner T. F. C. S.,
Ford C. N.,
Hafuz G. R.
Publication year - 1985
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1985.tb00451.x
Subject(s) - melanoma , pathology , enolase , biology , ultrastructure , medicine , immunohistochemistry , anatomy , cancer research
Neurotropic melanoma is a variant of desmoplastic melanoma which, in addition to a spindle‐cell vertical component and fibrosis, exhibits a lascicular growth pattern and invades cutaneous nerves. Here we describe a neurotropic melanoma which arose in a small Ientigo maligna melanoma and invaded the maxillary nerve for a distance of 5 cm. Ultrastructural features were similar to those of previously described neurotropic melanomas and tumor fascicles contained S‐100 protein and neuron‐specific enolase immunoreactivity.