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The origin of the adnexal tumors of the skin: a viewpoint
Author(s) -
Mehregan A. H.
Publication year - 1985
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1985.tb00444.x
Subject(s) - pathology , medicine , adnexal diseases , dermatology , radiology , laparoscopy
Histogenesis of adnexal tumors of the skin has not been the subject of an independent study or a publication since the theory of pluripotentiality of epithelial matrix cells was introduced and applied to the origin of adnexal tumors some 25 years ago. In this period, a number of new tumor entities have been described. Histologic studies as well as enzyme histochemistry, electron microscopy and, lately, the results of the application of monoclonal antibodies have provided a wealth of new information. In this article a review of the histogenesis of adnexal tumors is made and, based on clinical and histologic data provided, an alternative view for origin of adnexal tumors of the skin is proposed.