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Chrysiasis following gold therapy for rheumatoid arthritis: ultrastructural analysis with x‐ray energy spectroscopy
Author(s) -
Pelachyk J. M.,
Bergfeld W. F.,
McMahon J. T.
Publication year - 1984
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1984.tb00408.x
Subject(s) - rheumatoid arthritis , medicine , gold standard (test) , pathology , biopsy , ultrastructure , dermatology
Chrysiasis is a rare, permanent, pigmentation of the skin caused by the parenteral administration of gold preparations followed by subsequent exposure to ultraviolet light. We report a case of chrysiasis following gold therapy for rheumatoid arthritis, wherein ultrastructural analysis combined with x‐ray energy spectroscopy afforded precise identification and localization of the gold pigment in skin biopsy specimens.