Premium
Immunopathology of vitiligo vulgaris, Sutton's leukoderma and melanoma‐associated vitiligo in relation to steroid effects
Author(s) -
Uda H.,
Takei M.,
Mishima Y.
Publication year - 1984
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1984.tb00361.x
Subject(s) - vitiligo , dermatology , pathology , pigmentation disorder , medicine , basement membrane , thyroid
Microsome, thyroid and DNA tests on patients with generalized vitiligo vulgaris, with or without Sutton's leukoderma, show a high positive rate without thyroid diseases. A small, hut not negligible, amount of IgG and O deposits in the basement‐membrane zone and Keratinocytes, has been frequently seen in these diseases by immunohistoogy and immunoelectron microscopy. This evidence strongly suggests an autoimmune character for these diseases.