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Trichilemmal keratinization in seborrheic keratoses
Author(s) -
Masuda Mitsugi,
Kimura Shunji
Publication year - 1984
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1984.tb00344.x
Subject(s) - seborrheic keratosis , pathology , keratin , spongiosis , keratosis , dermatology , epidermis (zoology) , dermatopathology , medicine , anatomy
In 33 of 112 seborrheic keratoses reviewed histologically, a keratinization process was observed, which was identical with or showed marked similarity to, trichilemmal keratinization (TK). This type of keratinization took place more frequently in lesions which were pruritic and in those located on the extremities. Histologically, the change was observed in the bottoms of pseudocysts and crypts, in areas showing evidence of inflammation, such as exocytosis, spongiosis and squamous eddy or whorl formation. No relationship was found between the presence of TK or TK‐like keratinization and the various histologic types of seborrheic keratoses. It is concluded that a process which can not be distinguished from TK microscopically may occur frequently in seborrheic keratoses as a result of inflammation.