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Epidermotropism in Melanoma
Author(s) -
WARNER THOMAS F. C. S.,
GILBERT ENID F.,
RAMIREZ G.
Publication year - 1980
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1980.tb00977.x
Subject(s) - melanoma , medicine , pathology , malignant transformation , disease , parkinsonism , dermatology , cancer research
Multiple malignant melanocytic lesions developed in a 54‐year‐old man 4 years after a primary malignant melanoma (Clark level IV) had been excised and 2 months after taking L‐Dopa for Parkinsonism. Several of the recurrent lesions that showed junctional melanocytic components were considered primary melanomas and it was suggested that L‐Dopa was responsible for malignant transformation of nevi and for rapid progression of the disease. The case was re‐examined and on recent evidence it is likely that these lesions were epidermotropic metastases and that L‐Dopa played no part in the progress of this unusual tumor.