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Giant Cells in Male Pattern Alopecia: a Histologic Marker and Pathogenetic Clue
Author(s) -
DOMNITZ JEFFREY M.,
SILVERS DAVID N.
Publication year - 1979
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1979.tb01111.x
Subject(s) - multinucleate , giant cell , pathology , concomitant , biopsy , anatomical pathology , biology , medicine , immunohistochemistry
Twenty‐one of 65 (31%) biopsy specimens from patients with male pattern alopecia demonstrated the presence of individually displaced multinucleate giant cells without a significant concomitant cellular infiltrate. This finding was absent in a diverse group of other forms of alopecia. Whether individually displaced multinucleate cells are a useful histologic marker for diagnosing early stages of androgenetic alopecia remains to be determined.