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Melanoacanthoma
Author(s) -
SCHLAPPNER O. L. A.,
ROWDEN G.,
PHILLIPS T. M.,
RAHIM Z.
Publication year - 1978
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1978.tb00949.x
Subject(s) - pathology , melanoma , melanocyte , chemistry , biology , anatomy , medicine , cancer research
Electronmicroscopic studies confirmed that melanoacanthoma is a non‐nevoid elevated epithelial tumor composed of keratinocytes of both basaloid and spinous differentiation and of large dentritic melanocytes. The block in transfer of pigment from melanocytes to keratinocytes was found not to be complete. Langerhans cells, present in all the malpighian layers were normal in morphology. Immunofluorescent studies and an immunoprecipitin assay also showed our patient's melanoacanthoma not to be related to malignant melanoma.