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Immunofluorescence Studies in Scabies
Author(s) -
FRENTZ GERDA,
VEIEN NIELS K.,
ERIKSEN KNUD
Publication year - 1977
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1977.tb00907.x
Subject(s) - scabies , immunofluorescence , pathology , dermatology , medicine , immunology , antibody
Direct and indirect immunofluorescence investigations were performed for 11 patients with scabies. All patients had punch biopsies taken from (1) a lesion containing Sarcoptes scabiei , (2) an inflammatory papule which did not contain a mite, and (3) normal skin. In four patients lgE deposits were found in the vessel walls of the upper dermis both in biopsies containing mites and biopsies of inflammatory papules with no mites. No IgE deposits were found in biopsies of normal skin from the same patients. Two patients had IgM and/or C 3 deposits along the basal membrane in biopsies containing mites and one of them also had C 3 in this area in the biopsy from a papule with no mite, as well as in normal skin.