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Sebaceous Carcinoma of the Eyelid with Pagetoid Involvement of the Bulbar and Palpebral Conjunctiva
Author(s) -
LEE SIONG CHUAN,
ROTH LAWRENCE M.
Publication year - 1977
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1977.tb00899.x
Subject(s) - pagetoid , sebaceous carcinoma , pathology , conjunctiva , eyelid , epithelium , palpebral fissure , carcinoma , pilomatrixoma , biology , medicine , anatomy , immunohistochemistry , surgery
A case of sebaceous carcinoma with pagetoid involvement of the palpebral and bulbar conjunctival epithelium was studied by light and electron microscopy. Ultrastructurally, the neoplastic cells within the conjunctival epithelium were identical to those in the underlying invasive sebaceous carcinoma. Evidence of gradual transformation of conjunctival epithelial cells to the neoplastic sebaceous cells or transitional forms between conjunctival epithelial cells and sebaceous cells was not encountered. The evidence thus supports the theory that the neoplastic cells in the conjunctival epithelium are the result of secondary invasion by the underlying sebaceous carcinoma.