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Allergic contact dermatitis caused by isocyanates in resin jewellery
Author(s) -
Nguyen Rebecca,
Lee Adriene
Publication year - 2012
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.2012.02042.x
Subject(s) - allergic contact dermatitis , medical library , health department , medicine , library science , art history , sociology , art , nursing , public health , computer science , allergy , immunology
A 35-year-old female office worker attended a popular weekend course to develop her interest in making resin jewellery. This involved using a two-part polyurethane resin system that, according to the Material Safety Data Sheet (MSDS), contained 70–90% 4,4′dicyclohexylmethane-4,4′-diisocyanate (DMDI; CAS 5124-30-1). The two components were mixed, poured into a silicone mould, and allowed to set. On one occasion when the patient did not use gloves, her skin came into direct contact with the polyurethane mixture. The next day, she developed an acute pruritic eruption on her right index finger. Two weeks later, after further resin jewellery making, she developed a pruritic eczematous eruption on her face, neck, and hands. This resolved with topical and oral corticosteroids and avoidance of further jewellery making. There were no associated respiratory symptoms. She no longer undertakes any jewellery making, and has had no recurrences.